Advantage Multi is a broad-spectrum parasite treatment available in products for both dogs and cats. It works at various parasite life stages and can be used as an alternative to Revolution.
Advantage Multi for Dogs prevents heartworm disease, kills fleas (Ctenocephalides felis), and treats common intestinal parasites including roundworm, hookworm, and whipworm. It can also be used in the treatment and control of sarcoptic mange.
Advantage Multi for Cats kills adult and egg fleas and treats and controls ear mites, heartworms, hookworms, and roundworms. Advantage Multi for Cats has also been FDA approved for the treatment fleas and heartworm disease in ferrets over 2 pounds (0.9 kg).
Benefits
Topical treatment ensures the product is not refused
Dogs are protected from heartworm disease even after bathing (from 90 minutes after treatment)
Advantage Multi for Dogs is for use on dogs and puppies over 7 weeks of age and with a body weight of at least 3lbs (1.4kg) minimum.
Advantage Multi for Cats is for use on cats and kittens over 9 weeks of age and with a body weight of 2lbs (0.9kg) minimum.
Dosage Schedule
Advantage Multi is a topical treatment designed to be used once a month.
The dosage for both dogs and cats is based on the animal’s body weight - please ensure you have the correct product for your pet’s size.
Advantage Multi for Dogs
Body weight
Volume (ml)
Imidacloprid (mg)
Moxidectin (mg)
3-8.8 lbs (1.4-4 kg)
0.4
40
10
8.8-22 lbs (4-10 kg)
1
100
25
22-55 lbs (10-25 kg)
2.5
250
62.5
Over 55lbs (25 kg)
4
400
100
Advantage Multi for Cats
Body weight
Volume (ml)
Imidacloprid (mg)
Moxidectin (mg)
2-8.8 lbs (0.9-4 kg)
0.4
40
4
8.8-17.6 lbs (4-8 kg)
0.8
80
8
What are the side effects of Advantage Multi?
The most common reported side effects in dogs is pruritis. Residue and medicinal odor have also been reported.
Adverse reactions reported in cats include behavioral changes, discomfort, and lethargy. Excessive salivation and polydipsia have also been reported.
What precautions must be taken?
Do not administer orally – topical application only.
Wash hands thoroughly with soap and warm water after application.
Keep out of reach children and animals.
Not for human use.
Ensure the pet or other animals can not lick the area of application for 30 minutes after administration.
Advantage Multi for Dogs
Advantage Multi for Dogs should not be used on cats.
Not for use on dogs and puppies under 7 weeks of age or under 3lbs in weight.
Advantage Multi for Dogs has not been evaluated in heartworm-positive dogs with class 4 heartworm disease.
The safe use of Advantage Multi in breeding, pregnant or lactating dogs has not been evaluated.
Children should not come into contact with application sites for 2 hours after administration.
Advantage Multi for Cats
Advantage Multi for Cats should not be used on dogs.
Not for use on cats and kittens under 6 weeks of age or under 2lbs in weight.
The safe use of Advantage Multi in breeding, pregnant or lactating cats has not been evaluated.
The effective use of Advantage Multi for Cats against heartworm infections after bathing has not been evaluated in cats.
Children should not come into contact with application sites for 30 minutes after administration.
How effective is Advantage Multi (imidacloprid + moxidectin)?
Advantage Multi for Dogs: A 56-day field safety study was conducted in 214 D.immitis heartworm and microfilariae positive dogs with Class 1, 2 or 3 heartworm disease. All dogs received Advantage Multi for Dogs on Study Days 0 and 28; 108 dogs also received melarsomine dihydrochloride on Study Days – 14, 14, and 15. All dogs were hospitalized for a minimum of 12 hours following each treatment. Effectiveness against circulating D. immitis microfilariae was > 90 % at five of six sites; however, one site had an effectiveness of 73.3%. The microfilariae count in some heartworm-positive dogs increased or remained unchanged following treatment with Advantage Multi for Dogs alone or in a dosing regimen with melarsomine dihydrochloride.
